Metabolism of Drugs

Drug metabolism is a vital process that involves the biotransformation of drugs into metabolites that are more easily excreted from the body. The liver is the primary site of drug metabolism, where enzymes such as cytochrome P450 (CYP) play a significant role in catalyzing metabolic reactions. These enzymes can either activate or inactivate drugs, leading to changes in their pharmacological activity. Metabolism involves phase I and phase II reactions, where phase I reactions typically involve ox...