Genetic Basis of Disease

Genetics plays a pivotal role in understanding the underlying mechanisms of various diseases. Through advances in genomics, we have elucidated the genetic basis of inherited diseases such as cystic fibrosis, sickle cell anemia, and Huntington's disease. These diseases result from mutations in specific genes that lead to dysfunctional proteins or regulatory processes. For example, cystic fibrosis is caused by mutations in the CFTR gene, resulting in defective ion transport across cell membranes....